The same medicine family, in a daily tablet.

An honest comparison

Compounded oral semaglutide is not FDA-approved and is not the same product as the branded, FDA-approved semaglutide tablet. The large weight-loss trials people quote were run on injectable branded medicines, so those results should not be read as results for this tablet.

Tablets are absorbed through the stomach, so how much reaches your body varies more than with an injection. They need to be taken the same way every morning. Your provider will talk you through both options.

Important safety information

GLP-1 medications such as semaglutide and tirzepatide are prescription medicines. Compounded versions are prepared by licensed pharmacies and are not FDA-approved. They have not been reviewed by the FDA for safety, effectiveness or quality.

Do not use if you or a family member have had medullary thyroid carcinoma, if you have Multiple Endocrine Neoplasia syndrome type 2, or if you are pregnant, planning pregnancy or breastfeeding. In studies in rodents, these medicines caused thyroid C-cell tumors; it is not known whether they cause them in people.

Common side effects include nausea, vomiting, diarrhea, constipation, stomach pain and reduced appetite. Serious side effects can include pancreatitis, gallbladder problems, low blood sugar when used with some diabetes medicines, kidney problems, allergic reactions and changes in vision in people with diabetes.

Tell your provider about every medicine you take. Stop and seek medical care right away if you have severe stomach pain that does not go away, swelling of the face or throat, or trouble breathing.

Questions women ask us